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Acetonitrile (ACN) is a high-purity polar aprotic solvent supplied by Alkemist KSA. As a leading wholesale dealer, we provide industrial and HPLC-grade Acetonitrile, which is indispensable in analytical chemistry, particularly for High-Performance Liquid Chromatography (HPLC). It is also a vital solvent in the pharmaceutical industry and for DNA synthesis.
DANGER: HIGHLY FLAMMABLE & HARMFUL. Acetonitrile is a highly flammable liquid. It is harmful if swallowed, inhaled, or in contact with skin. It can cause serious eye irritation. Always use in a well-ventilated area with proper personal protective equipment (PPE), including an organic vapor respirator, chemical-resistant gloves, and safety goggles. Request the MSDS for full safety details.
Acetonitrile is favored for High-Performance Liquid Chromatography (HPLC) because it has a low viscosity (allowing for lower backpressure), is miscible with water, and has a low UV cutoff, which means it doesn't interfere with the detection of many compounds being analyzed.
HPLC Grade means the solvent has been manufactured and tested to meet extremely high purity standards. It is free from impurities that could interfere with sensitive analytical tests, ensuring accurate and reproducible results in a laboratory setting.
Yes, Acetonitrile is an effective polar aprotic solvent, meaning it can dissolve a wide range of polar and non-polar compounds. This versatility makes it useful not only in analytical labs but also as a process solvent in the pharmaceutical and chemical industries.
In the automated synthesis of DNA and RNA, Acetonitrile is used as the primary solvent to dissolve the chemical building blocks (phosphoramidites) and to wash the growing DNA/RNA chain between reaction steps, ensuring a high-purity final product.
Acetonitrile is highly flammable and toxic. It can be absorbed through the skin and is harmful if inhaled or swallowed. It is essential to work in a fume hood or a very well-ventilated area and to use appropriate PPE, including chemical-resistant gloves (like butyl rubber) and safety goggles.